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Incretin-receptor research peptides

Incretin-receptor peptides for laboratory research: Semaglutide, Tirzepatide and Retatrutide, plus related compounds. Research use only.

Quick answer

Incretin-receptor research peptides are tool compounds used in laboratory studies of incretin and glucagon receptor signaling. The category spans three receptor profiles: Semaglutide, a GLP-1 receptor agonist; Tirzepatide, a dual GIP and GLP-1 receptor agonist; and Retatrutide, an agonist of the GIP, GLP-1 and glucagon receptors. USA Warehouse Supply also lists 5-Amino-1MQ and the KLOW Blend in this category. Every product is for research use only.

Tirzepatide 20mg research vial
Bestseller
Tirzepatide
Dual GIP and GLP-1 receptor agonist peptide
$40
Retatrutide 10mg research vial
Bestseller
Retatrutide
Triple-agonist incretin reference peptide
$55
KLOW Blend 80mg research vial
Bestseller
KLOW Blend
Multi-component research blend, one 80mg vial
$90
Semaglutide 15mg research vial
Semaglutide
Acylated GLP-1 receptor agonist peptide
$60
5-Amino-1MQ 5mg research vial
Out of stock
5-Amino-1MQ
Small-molecule NNMT inhibitor for research
$35
Sold out

Questions

What is the difference between semaglutide, tirzepatide and retatrutide?
Receptor coverage. Semaglutide acts on the GLP-1 receptor. Tirzepatide acts on the GIP and GLP-1 receptors, with greater engagement of the GIP receptor in published pharmacology. Retatrutide acts on the GIP, GLP-1 and glucagon receptors.
Are these vials for human or animal use?
No. They are sold for laboratory work only, not for human or animal use.
How are the lyophilized vials stored?
A published peptide handling guide stores lyophilized peptide at -20 °C, keeps peptides away from direct light and lets the vial warm to room temperature, ideally in a desiccator, before dissolving. It also recommends single-use aliquots on receipt and no repeated freezing and thawing.
How do orders ship?
Every order ships from the U.S. after payment is confirmed. We email your tracking number as soon as the shipping label is created.

How do GLP-1, dual and triple agonist peptides differ?

They differ in which receptors they act on. Semaglutide is a GLP-1 analog with a fatty acid and linker that bind albumin reversibly while it keeps GLP-1 receptor potency. Tirzepatide is a dual GIP and GLP-1 receptor agonist; published pharmacology describes greater engagement of the GIP receptor and, at the GLP-1 receptor, a bias toward cAMP generation over beta-arrestin recruitment. Retatrutide adds the glucagon receptor, acting on GIP, GLP-1 and glucagon receptors.

SemaglutideTirzepatideRetatrutide