
Retatrutide
Retatrutide is a synthetic 39-residue peptide engineered to co-activate the GLP-1, GIP, and glucagon receptors, with C20 fatty-diacid acylation for extended plasma stability. It is a reference compound in pre-clinical incretin and metabolic-signaling research.
A benchmark tool compound for poly-agonist incretin pharmacology.
What it is
Retatrutide is a 39-amino-acid synthetic peptide engineered to co-activate the GLP-1, GIP, and glucagon receptors. A C20 fatty-diacid moiety promotes albumin binding and a long plasma half-life.
It is used as a reference compound in pre-clinical incretin pharmacology to benchmark single- versus poly-receptor response curves. For laboratory research only.
Reconstitution & storage
- Reconstitute with bacteriostatic water — add slowly down the vial wall and swirl gently; do not shake.
- Store lyophilized vials at -20°C; once reconstituted keep at 2–8°C and use within ~4 weeks.
- Protect from light and avoid repeated freeze–thaw cycles.
Cited research applications
Questions
Related compounds
For Research Use Only. Not for human or animal consumption. This product has not been evaluated by the Food and Drug Administration. Not intended to diagnose, treat, cure, or prevent any disease. Retatrutide is sold strictly as a research chemical for in-vitro and pre-clinical laboratory investigation only.


