
MOTS-c
MOTS-c is a 16-residue peptide encoded by the mitochondrial 12S rRNA region. It is the headline reference compound for mitochondrial-derived-peptide and AMPK-pathway signaling research.
The benchmark mitochondrial-derived peptide for AMPK-pathway studies.
What it is
MOTS-c (Mitochondrial ORF of the Twelve-S rRNA type-c) is a 16-amino-acid peptide encoded within the mitochondrial genome — one of the best-characterized mitochondrial-derived peptides.
It is studied as a tool compound in AMPK-pathway signaling, metabolic-homeostasis models, and exercise-biology research. Supplied for laboratory use only.
Reconstitution & storage
- Reconstitute with bacteriostatic water — add slowly down the vial wall and swirl gently; do not shake.
- Store lyophilized vials at -20°C; once reconstituted keep at 2–8°C and use within ~4 weeks.
- Protect from light and avoid repeated freeze–thaw cycles.
Cited research applications
Questions
Related compounds
For Research Use Only. Not for human or animal consumption. This product has not been evaluated by the Food and Drug Administration. Not intended to diagnose, treat, cure, or prevent any disease. MOTS-c is sold strictly as a research chemical for in-vitro and pre-clinical laboratory investigation only.

