Somatotropic research peptides
GHRH analogs and growth hormone secretagogues for somatotropic-axis research: CJC-1295, Tesamorelin and Ipamorelin. Research use only.
Somatotropic research peptides are tool compounds used in laboratory studies of the growth hormone axis. They fall into two groups. GHRH analogs, such as CJC-1295 and Tesamorelin, are modified forms of growth hormone-releasing hormone. Growth hormone secretagogues, such as Ipamorelin, act through a GHRP-like receptor instead. The category also lists a combined CJC-1295 + Ipamorelin vial. For research use only.
Questions
What is the difference between a GHRH analog and a GH secretagogue?
GHRH analogs and growth hormone secretagogues reach growth hormone release by different routes. GHRH analogs are modified forms of growth hormone-releasing hormone: Tesamorelin is human GRF(1-44) amide with a trans-3-hexenoyl group that resists dipeptidyl aminopeptidase-IV, and CJC-1295 binds albumin covalently through a reactive maleimidopropionic acid group, extending its duration of action. Ipamorelin is a synthetic pentapeptide secretagogue that acts through a GHRP-like receptor, described in 1998 as a selective growth hormone secretagogue.




